| 세션명 | 대학원생 구두발표(토론II): 생체고분자 기반 의료공학 기술 |
|---|---|
| 발표장 | 제8-2회장 |
| 논문코드 | OD2-3 |
| 발표일 | 2024-04-3 |
| 발표시간 | 13:20-13:30 |
| 논문제목 | Substrate-Independent Antifouling and Biocidal Hydrogel Coatings Synthesized by Visible Light Cross-Linking |
| 발표자 | 노순종 |
| 발표자 소속 | 서울대학교, 한국과학기술연구원 |
| 저자 | 노순종, 이강원1,†, 류진2, 정영미2 |
| 소속 | 서울대학교, 한국과학기술연구원; 1서울대학교; 2한국과학기술연구원 |
| 논문초록 | Biofouling and bacterial infections are significant challenges in the use of biomedical materials, often leading to severe inflammation in the body by biofilm formation on implant surfaces. Addressing this, we propose a dual-functional hydrogel coating with synergetic antifouling and biocidal properties to prevent the initial infection and consequent biofilm formation. This coating is fabricated via photo-crosslinking, combining representative zwitterionic polymer, poly(sulfobetaine methacrylate) (pSBMA), with a cationic biocidal polymer, poly(2-aminoethyl methacrylate) (pAEMA). Our results demonstrate that the hydrogel coating exhibits excellent biocompatibility and applicability to various substrate materials. The surface coated with p(SBMA@AEMA) hydrogel displays significant antifouling and bactericidal activities. The developed coating method holds great potential for enhancing the performance and safety of various implantable biomaterials and medical devices. |
THE POLYMER SOCIETY OF KOREA